Ambro Bryan T, Zimmerman Jeffrey, Rosenthal Marc, Pribitkin Edmund A
Department of Otolaryngology -- Head and Neck Surgery, Thomas Jefferson University, Philadelphia, Pa 19107, USA.
Arch Facial Plast Surg. 2003 Nov-Dec;5(6):528-9. doi: 10.1001/archfaci.5.6.528.
Repair of nasal septal perforations presents a difficult challenge to the otolaryngologist. Successful closure rates of greater than 90% have been published by several authors using bipedicled mucoperichondrial advancement flaps and interpositional grafts. A number of different materials, both autografts and allografts, have been used as interpositional grafts. We report a 100% closure rate (10 of 10) using an open rhinoplasty technique with bipedicled advancement flaps and porcine small intestinal submucosa (SurgiSIS; Cook Biotech Inc, West Lafayette, Ind) as an interpositional graft. We submit that SurgiSIS is an ideal material for use in the repair of nasal septal perforations because it is easy to work with, demonstrates the ability to support the regeneration of adjacent tissue, and avoids the increased operative time and morbidity associated with harvesting autografts.
鼻中隔穿孔的修复对耳鼻喉科医生来说是一项艰巨的挑战。几位作者使用双蒂黏膜软骨膜推进皮瓣和植入移植物，发表了成功率超过90%的报告。许多不同的材料，包括自体移植物和同种异体移植物，都被用作植入移植物。我们报告了使用开放式鼻整形术技术、双蒂推进皮瓣和猪小肠黏膜下层（SurgiSIS；库克生物技术公司，印第安纳州西拉斐特）作为植入移植物的100%闭合率（10例中的10例）。我们认为SurgiSIS是用于修复鼻中隔穿孔的理想材料，因为它易于操作，显示出支持相邻组织再生的能力，并且避免了与采集自体移植物相关的手术时间增加和发病率。
