Ludwig Andrea A, Romeis Tina, Jones Jonathan D G
The Sainsbury Laboratory, John Innes Centre, Colney Lane, Norwich NR4 7UH, UK.
J Exp Bot. 2004 Jan;55(395):181-8. doi: 10.1093/jxb/erh008. Epub 2003 Nov 17.
Plants are constantly exposed to environmental changes and have to integrate a variety of biotic and abiotic stress stimuli. Calcium-dependent protein kinases (CDPKs) are implicated as important sensors of Ca2+ flux in plants in response to these stresses. CDPKs are encoded by multigene families, and expression levels of these genes are spatially and temporally controlled throughout development. In addition, a subset of CDPK genes responds to external stimuli. Biochemical evidence supports the idea that CDPKs are involved in signal transduction during stress conditions. Furthermore, loss-of-function and gain-of-function studies revealed that signalling pathways leading to cold, salt, drought or pathogen resistance are mediated by specific CDPK isoforms
植物不断暴露于环境变化中，必须整合各种生物和非生物胁迫刺激。钙依赖性蛋白激酶（CDPKs）被认为是植物中响应这些胁迫时Ca2+通量的重要传感器。CDPKs由多基因家族编码，这些基因的表达水平在整个发育过程中受到时空控制。此外，一部分CDPK基因对外部刺激有反应。生化证据支持CDPKs在胁迫条件下参与信号转导的观点。此外，功能丧失和功能获得研究表明，导致抗寒、抗盐、抗旱或抗病的信号通路由特定的CDPK亚型介导。
