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癌症:一种具有多种表现形式的单一疾病?

Cancer: a single disease with a multitude of manifestions?

作者信息

Grandics Peter

机构信息

A-D Research Foundation, 5922 Farnsworth Ct, Carlsbad, CA 92008 USA.

出版信息

J Carcinog. 2003 Nov 18;2(1):9. doi: 10.1186/1477-3163-2-9.

Abstract

The relationships of critical nutrients such as plant phenolics, vitamins, minerals and lipids are considered with respect to the incidence of a variety of cancers, and analyzed in terms of how these nutrient deficiencies alter immune function, DNA integrity and cell proliferation. With a significant correlation found between cancer and these nutrient deficiencies, the hypothesis is presented here that nutrition could provide a unifying perception of cancer and recast it as a single disease. This further suggests that a coordinated administration of specific, critical nutrients to cancer patients could lead to the reversal of the disease. It is also proposed that the concurrent presence of a variety of nutritional deficiencies in cancer patients requires a multilevel, systemic approach to this disease as opposed to the single active therapeutic agent approach that is the cornerstone of contemporary research and pharmacology.

摘要

研究了植物酚类、维生素、矿物质和脂质等关键营养素与多种癌症发病率之间的关系,并分析了这些营养素缺乏如何改变免疫功能、DNA完整性和细胞增殖。鉴于癌症与这些营养素缺乏之间存在显著相关性,本文提出一个假说,即营养可以为癌症提供统一的认知,并将其重新定义为一种单一疾病。这进一步表明,对癌症患者协同施用特定的关键营养素可能会使疾病得到逆转。还提出,癌症患者同时存在多种营养缺乏的情况,需要采用多层次、系统性的方法来应对这种疾病,而不是采用当代研究和药理学的基石——单一活性治疗药物的方法。

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本文引用的文献

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