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自发性双侧症状性椎动脉夹层的血管内治疗

Endovascular management of spontaneous bilateral symptomatic vertebral artery dissections.

作者信息

Cohen José E, Gomori John Moshe, Umansky Felix

机构信息

Department of Neurosurgery, Hadassah University Hospital, Jerusalem, Israel.

出版信息

AJNR Am J Neuroradiol. 2003 Nov-Dec;24(10):2052-6.

Abstract

Extracranial vertebral artery (VA) dissection may lead to significant arterial stenosis, occlusion, or pseudoaneurysm formation with subsequent hemodynamic and embolic infarcts. To prevent thromboembolic complications, anticoagulation with intravenous heparin followed by oral warfarin has been recommended for all patients with acute dissections, regardless of the type of symptoms. Nevertheless, anticoagulation is not innocuous and may be associated with hemorrhagic transformation of a cerebral infarction or may be ineffective to prevent symptoms or dissection progression. We present a case of a bilateral spontaneous extracranial VA dissection presenting with multiple embolic infarctions. The dominant VA was reconstructed with multiple in-tandem stents and the contralateral VA, proved to be the source of emboli, was occluded with coils. Stent-assisted VA angioplasty has rarely been reported in the management of spontaneous dissections and appears to be a safe, effective and immediate method of restoring vessel lumen integrity and should be considered in the therapy of selected cases of VA dissection.

摘要

颅外椎动脉(VA)夹层可能导致显著的动脉狭窄、闭塞或假性动脉瘤形成,继而引发血流动力学和栓塞性梗死。为预防血栓栓塞并发症,对于所有急性夹层患者,无论症状类型如何,均推荐先静脉注射肝素抗凝,随后口服华法林。然而,抗凝并非毫无风险,可能与脑梗死的出血性转化相关,或者在预防症状或夹层进展方面可能无效。我们报告一例双侧自发性颅外VA夹层伴多发栓塞性梗死的病例。对优势侧VA采用多个串联支架进行重建,而对侧VA被证实为栓子来源,用弹簧圈进行了闭塞。支架辅助VA血管成形术在自发性夹层的治疗中鲜有报道,似乎是一种恢复血管腔完整性的安全、有效且即时的方法,在VA夹层的特定病例治疗中应予以考虑。

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