Go M R, Muscarella P, Needleman B J, Cook C H, Melvin W S
Department of Surgery, The Ohio State University Medical Center, 410 W. 10th Avenue, Columbus, OH 43210, USA.
Surg Endosc. 2004 Jan;18(1):56-9. doi: 10.1007/s00464-003-8919-x. Epub 2003 Nov 21.
In the United States, Roux-en-Y gastric bypass has evolved into the procedure of choice for clinically severe obesity. Stomal stenosis resulting in gastric outlet obstruction is a recognized complication. Endoscopic balloon dilation is often used to treat this condition. To evaluate the safety and efficacy of endoscopic management of stomal stenosis we evaluated our treatment methods and outcomes.
The records of all patients undergoing Roux-en-Y gastric bypass from 1 July 2000 to 30 June 2002 were studied. Stenosis was defined as signs and symptoms of obstruction with inability to cannulate the gastrojejunostomy using an 8.5-mm diagnostic endoscope. Charts were reviewed and demographic data, operative course, symptoms, and outcomes were recorded.
A total of 562 patients underwent Roux-en-Y gastric bypass for obesity during the study period. Of these, 38 patients underwent endoscopic balloon dilation for stomal stenosis, for a stenosis rate of 6.8%. The average time from surgery to initial dilation was 7.7 weeks (range 3 to 24). The average number of dilations required was 2.1 (range one to six). The mean initial balloon size was 13 mm and the mean final balloon size was 16 mm. Two patients failed endoscopic dilation and proceeded to surgery, including one patient who developed pneumomediastinum and pneumothorax after dilation. All patients were relieved of their gastric outlet obstruction. The success rate for endoscopic balloon dilation was 95% with a 3% complication rate.
In our experience, the rate of gastrojejunostomy stenosis following Roux-en-Y gastric bypass is 6.8%. Endoscopic balloon dilation is a safe and effective therapy for stomal stenosis with a high success rate. It should be considered an appropriate intervention with a low risk for reoperation.
在美国,Roux-en-Y胃旁路术已成为临床严重肥胖症的首选手术方式。导致胃出口梗阻的吻合口狭窄是一种公认的并发症。内镜下球囊扩张术常被用于治疗这种情况。为了评估内镜治疗吻合口狭窄的安全性和有效性,我们对我们的治疗方法和结果进行了评估。
研究了2000年7月1日至2002年6月30日期间所有接受Roux-en-Y胃旁路术的患者的记录。狭窄定义为梗阻的体征和症状,且使用8.5毫米诊断性内镜无法插入胃空肠吻合口。查阅病历并记录人口统计学数据、手术过程、症状和结果。
在研究期间,共有562例患者因肥胖接受了Roux-en-Y胃旁路术。其中,38例患者因吻合口狭窄接受了内镜下球囊扩张术,狭窄发生率为6.8%。从手术到首次扩张的平均时间为7.7周(范围为3至24周)。所需扩张的平均次数为2.1次(范围为1至6次)。初始球囊的平均大小为13毫米,最终球囊的平均大小为l6毫米。2例患者内镜扩张失败并接受了手术,其中1例患者在扩张后出现了纵隔气肿和气胸。所有患者的胃出口梗阻均得到缓解。内镜下球囊扩张术的成功率为95%,并发症发生率为3%。
根据我们的经验,Roux-en-Y胃旁路术后胃空肠吻合口狭窄的发生率为6.8%。内镜下球囊扩张术是治疗吻合口狭窄的一种安全有效的方法,成功率高。它应被视为一种合适的干预措施,再次手术风险低。