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药学院学生的血浆胆固醇浓度、膳食脂肪摄入量和胆固醇摄入量。

Plasma cholesterol concentrations, dietary fat intake, and cholesterol intake in pharmacy students.

作者信息

Spinler Sarah A, de Denus Simon, Earl Grace, Cheng Judy W

机构信息

Philadelphia College of Pharmacy, University of the Sciences in Philadelphia, 600 S. 43rd Street, Philadelphia, PA 19104, USA.

出版信息

J Am Pharm Assoc (2003). 2003 Sep-Oct;43(5):590-5. doi: 10.1331/154434503322452229.

Abstract

OBJECTIVE

To evaluate the impact of formal education on hyperlipidemia on pharmacy students' dietary fat consumption and plasma cholesterol concentrations over a 3-month period.

DESIGN

Prospective, open, nonrandomized, controlled trial.

SETTING

College of pharmacy.

PARTICIPANTS

First professional-year (P1) and second professional-year (P2) pharmacy students.

INTERVENTION

P2 students received 6 hours of formal education regarding cardiovascular risk factors and National Cholesterol Education Program guidelines for detection and treatment of hyperlipidemia.

MAIN OUTCOME MEASURES

Percentage of total caloric intake from fat and saturated fat and plasma cholesterol concentrations after 1 and 3 months.

RESULTS

Significant differences were found between the percentage of total caloric intake from total and saturated fat for P1 and P2 students at all time points, with P1 > P2. A significant time effect was also found for percentage of total caloric intake from total and saturated fat as well as dietary cholesterol consumption for both groups, indicating no net effect of the formal educational intervention. No differences were found in average percentage of total caloric intakes from total and saturated fat between our student sample and that of a national sample of Americans of similar age from the National Health and Nutrition Examination Survey Series III (NHANES III). Female pharmacy students appeared to have lower plasma cholesterol concentrations than women of the same age group in the general American population.

CONCLUSION

Formal education did not alter students' percentage of total caloric intake from total and saturated fat or plasma cholesterol concentrations. Approximately 20% of pharmacy students may be eligible for more intensive diet and, perhaps, drug therapy for treatment of hypercholesterolemia.

摘要

目的

评估关于高脂血症的正规教育对药学专业学生在3个月期间饮食脂肪摄入和血浆胆固醇浓度的影响。

设计

前瞻性、开放性、非随机对照试验。

地点

药学院。

参与者

药学专业一年级(P1)和二年级(P2)学生。

干预措施

P2学生接受了6小时关于心血管危险因素以及国家胆固醇教育计划中高脂血症检测与治疗指南的正规教育。

主要观察指标

1个月和3个月后脂肪和饱和脂肪占总热量摄入的百分比以及血浆胆固醇浓度。

结果

在所有时间点,P1和P2学生的总脂肪和饱和脂肪占总热量摄入的百分比存在显著差异,P1>P2。两组学生的总脂肪、饱和脂肪占总热量摄入的百分比以及膳食胆固醇摄入量也存在显著的时间效应,表明正规教育干预没有净效应。我们的学生样本与来自第三次国家健康和营养检查调查系列(NHANES III)的年龄相仿的美国全国样本相比,总脂肪和饱和脂肪占总热量摄入的平均百分比没有差异。药学专业女学生的血浆胆固醇浓度似乎低于美国普通人群中同年龄组的女性。

结论

正规教育并未改变学生总脂肪和饱和脂肪占总热量摄入的百分比或血浆胆固醇浓度。约20%的药学专业学生可能适合接受更强化的饮食治疗,或许还包括药物治疗以控制高胆固醇血症。

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