Miyazono M, Iwaki T, Tateishi J, Fukui M
Department of Neuropathology, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Acta Neuropathol. 1992;84(5):577-80. doi: 10.1007/BF00304479.
A 45-year old immunocompetent man presented with multiple lesions in the brain. A histological examination of the tumors showed a diffuse infiltrate of lymphoid cells with cellular polymorphism and of multinucleated giant cells. These cells were immunolabeled with antibodies against B cell lineage and with a monoclonal antibody, Ber-H2 (CD30), which showed the presence of Ki-1 antigen. Recently, among systemic non-Hodgkin's lymphomas, attention has been given to Ki-1-positive lymphomas, which have been incorporated in the up-dated Kiel classification. We report here a case of Ki-1-positive lymphoma arising in the CNS and review previously reported cases.
