Jones T H, Figueroa C D, Smith C M, Bhoola K D
University Department of Medicine, Northern General Hospital, Sheffield, UK.
Agents Actions Suppl. 1992;38 ( Pt 2):175-82.
Tissue kallikrein (TK) is present and co-localises with prolactin producing cells in human prolactinoma and mixed growth hormone (GH) and prolactin-secreting pituitary adenomas. TK immunoreactivity was reduced or absent in these types of adenomas from patients who had received the dopamine agonist, bromocriptine before surgery. Pure GH secreting adenomas had no TK immunoreactivity.
组织激肽释放酶（TK）存在于人类催乳素瘤以及混合性生长激素（GH）和催乳素分泌型垂体腺瘤中，并与产生催乳素的细胞共定位。在术前接受过多巴胺激动剂溴隐亭治疗的患者的这些类型腺瘤中，TK免疫反应性降低或缺失。纯GH分泌型腺瘤没有TK免疫反应性。
