Nagarajan Lakshmi, Kulkarni Alpana, Palumbo-Clark Linda, Gregory Pauline Bernadette, Walsh Peter John, Gubbay Sasson Stephen, Silberstein Jonathon Michael, Silberstein Ernst Peter, Carty Emma Louise, Dimitroff Wendy Rosemary
Department of Neurology, Princess Margaret Hospital for Children, Perth, Australia.
Pediatr Neurol. 2003 Sep;29(3):222-6. doi: 10.1016/s0887-8994(03)00207-8.
This study evaluates the characteristics of photoparoxysmal responses elicited with intermittent photic stimulation during a routine electroencephalogram in childhood and correlated this with the clinical profile of the child. Photoparoxysmal responses occurred in 8% (21/263) of children where activation was undertaken. Photoparoxysmal responses were often brief and had a variable onset latency. This study suggests increasing the duration of the stimulus train to 10 seconds or more will increase the diagnostic yield. Photoparoxysmal responses very rarely outlasted the stimulus, and self-limited photoparoxysmal responses probably have greater significance than previously attributed to them. They are highly correlated with epilepsy.
本研究评估了儿童常规脑电图检查期间间歇性光刺激引发的光阵发性反应的特征，并将其与儿童的临床特征相关联。在进行激活操作的儿童中，8%（21/263）出现了光阵发性反应。光阵发性反应通常短暂，起始潜伏期可变。本研究表明，将刺激序列的持续时间增加到10秒或更长时间将提高诊断率。光阵发性反应很少超过刺激时间，自限性光阵发性反应可能比以前认为的具有更大的意义。它们与癫痫高度相关。
