Davidson Negraes Priscilla, Quinzani Jordão Berenice, Vicentini Veronica Elisa Pimenta, Mantovani Mário Sérgio
Universidade Estadual de Londrina, Departamento de Biologia Geral, Campus Universitario CP 6001, Laboratório de Mutagênese in vitro, Parana 86051 990, Brazil.
Toxicol In Vitro. 2004 Feb;18(1):147-9. doi: 10.1016/j.tiv.2003.07.001.
Chlorophyllin, a sodium-copper salt derivative of chlorophyll-a and -b, was evaluated for antimutagenic activity against ethyl methane sulfonate by the hypoxanthin-guanine-phosphoribosyl transferase (HGPRT) assay. The results obtained suggest that this chlorophyllin can potentiate the mutagenicity of an alkylating agent which induces DNA damage.
叶绿素铜钠盐，一种叶绿素a和b的铜钠盐衍生物，通过次黄嘌呤-鸟嘌呤-磷酸核糖转移酶（HGPRT）试验评估其对甲磺酸乙酯的抗诱变活性。所得结果表明，这种叶绿素铜钠盐可增强诱导DNA损伤的烷基化剂的诱变性。
