Liu Wenbin, Wang Shudong, Gao Lin, Zhang Fengyue, Xu Jin
Department of Control Science and Engineering, Huazhong University of Science and Technology, Wuhan City 430074, China.
J Chem Inf Comput Sci. 2003 Nov-Dec;43(6):2014-8. doi: 10.1021/ci025645s.
In DNA based computation and DNA nanotechnology, the design of proper DNA sequences has turned out to be an elementary problem. This paper takes a further look at the template strategy proposed in work by Frutos, A. G. et al. (Nucleic Acids Res. 1997, 25, 4748-4757). The H-measure proposed by Garzon et al. (Proceedings of the Second Annual Genetic Programming Conference, 1997; pp 472-487) is combined in this strategy to optimize the template and map sets obtained. Finally we describe a constructing method that can still produce more sequences by the results obtained in this paper.
在基于DNA的计算和DNA纳米技术中，设计合适的DNA序列已成为一个基本问题。本文进一步探讨了弗鲁托斯等人（《核酸研究》，1997年，第25卷，4748 - 4757页）工作中提出的模板策略。加尔松等人（《第二届年度遗传编程会议论文集》，1997年；第472 - 487页）提出的H度量被结合到该策略中，以优化获得的模板和映射集。最后，我们描述了一种构建方法，该方法仍可根据本文获得的结果生成更多序列。
