Kann J, Spiegelhalder B, Eisenbrand G, Preussmann R
Z Krebsforsch Klin Onkol Cancer Res Clin Oncol. 1977 Dec 15;90(3):321-3. doi: 10.1007/BF00284306.
46 samples of commercially available diets for experimental animals have been analysed for their content of volatile N-nitrosamines by use of a nitrosamine-specific detection method (TEA-detector). 80% of all analysed samples were positive for N-nitrosodimethylamine with a maximum content of 79 ppb (microgram/kg) found in one sample. 59% of the samples were positive for N-nitrosopyrrolidine with 26 ppb as highest content. In 3 samples trace quantities (less than 1 ppb) of N-nitrosodiethylamine were found, one sample contained N-nitrosopiperidine (4 ppb).
采用亚硝胺特异性检测方法(TEA 检测器)对 46 份市售实验动物饲料样本的挥发性 N - 亚硝胺含量进行了分析。在所有分析样本中,80%的样本检测出 N - 二甲基亚硝胺呈阳性,其中一个样本含量最高,达 79 ppb(微克/千克)。59%的样本检测出 N - 亚硝基吡咯烷呈阳性,最高含量为 26 ppb。在 3 个样本中发现了痕量(低于 1 ppb)的 N - 二乙基亚硝胺,一个样本含有 N - 亚硝基哌啶(4 ppb)。