苄基硝基脲（BzNH）对BD大鼠的致癌活性（作者译）
[Carcinogenic activity of benzyl-nitrosourea (BzNH) in BD-rats (author's transl)].
作者信息
Ivankovic S
出版信息
Z Krebsforsch Klin Onkol Cancer Res Clin Oncol. 1978 Jan 26;91(1):63-8. doi: 10.1007/BF00305973.
PMID:146343
Abstract
Chronic weekly oral and subcutaneous administration of N-Benzyl-N-nitrosourea induced carcinomas of the forestomach and local s.c. sarcomas respectively in BD-rats. This confirms a local carcinogenic effect of the compound. In prenatal experiments in BD-rats no carcinogenic effect of BzNH could be found.
摘要
每周对BD大鼠进行一次慢性口服和皮下注射N-苄基-N-亚硝基脲，分别诱发了前胃癌和局部皮下肉瘤。这证实了该化合物的局部致癌作用。在BD大鼠的产前实验中，未发现BzNH有致癌作用。
Zotero 插件