Leike J, Hühn U
Forschungszentrum für Tierproduktion Dummerstorf-Rostock, Bereich Fortpflanzung.
Berl Munch Tierarztl Wochenschr. 1992 Oct 1;105(10):345-9.
The trials were conducted on a pig farm (German Landrace) over a period of about two years. This farm worked in 7-day cycles using artificial insemination. In trial 1, 209 sows were treated with the prostaglandin F2 alpha analog Cloprostenol (Cloprostenol Jenapharm, 87.5 micrograms i.m.). In trial 2, 646 sows were divided into two groups. Both groups were treated with 100 micrograms Cloprostenol Jenapharm not earlier than on the 113th day of gestation (day 1 of gestation = the day after the first insemination). 24 h later, 119 sows received an additional injection of 1 ml of an oxytocin analog (Depotocin inj. Spofa, 1 ml contains 0.2 mg Carbetocin). In the other group, 120 sows received 2 ml Depotocin. This additional treatment with Depotocin resulted in a mean interval from the injection to the onset of farrowing of 125 minutes (gilts) and 49 minutes (sows). In trial 2, 97.9% of the sows farrowed within 30 hours after Cloprostenol injection (= partus rate 30). The additional treatment with Depotocin resulted in a shortening of farrowing periods, a reduction in mean expulsion time and effected an increase in farrowing during the day time. All these effects were significant (p < or = 0.05).
这些试验在一个养猪场（德国长白猪）进行，为期约两年。该养猪场采用人工授精，以7天为一个周期。在试验1中，209头母猪用前列腺素F2α类似物氯前列醇（氯前列醇，耶拿药厂生产，87.5微克，肌肉注射）进行治疗。在试验2中，646头母猪被分为两组。两组均在妊娠第113天（妊娠第1天 = 首次授精后的第二天）或之后用100微克耶拿药厂生产的氯前列醇进行治疗。24小时后，119头母猪额外注射1毫升催产素类似物（Depotocin inj.，Spofa生产，1毫升含0.2毫克卡贝缩宫素）。另一组120头母猪注射2毫升Depotocin。额外注射Depotocin导致从注射到开始分娩的平均间隔时间为125分钟（后备母猪）和49分钟（经产母猪）。在试验2中，97.9%的母猪在注射氯前列醇后30小时内分娩（= 30小时分娩率）。额外注射Depotocin缩短了分娩时间，减少了平均排出时间，并使白天分娩的数量增加。所有这些影响均具有显著性（p≤0.05）。
