Gill Chandler, Covington Cassondra, Padaliya Bimal, Newman William, Pomeroy Terri, Charles P David
Department of Neurology, Vanderbilt University Medical Center, Suite 304, Medical Center South, Nashville, TN 37212, USA.
Tenn Med. 2003 Nov;96(11):511-3.
Spasticity resulting from cerebral palsy can reduce the quality of life in affected children and can eventually cause more severe impairments, such as joint dislocation and scoliosis. Botulinum toxin type A (Botox) is widely used to temporarily alleviate the increased muscle tone associated with spasticity, and when combined with a comprehensive physical therapy regimen can result in permanent improvement. This report documents the successful use of Botox over a two-year period to treat spasticity secondary to cerebral palsy in a preschool-age child. Botox was used in conjunction with a specific physical therapy regimen in order to reach a functional goal of independent ambulation.
脑瘫导致的痉挛会降低患病儿童的生活质量，并最终导致更严重的损伤，如关节脱位和脊柱侧弯。A型肉毒杆菌毒素（保妥适）被广泛用于暂时缓解与痉挛相关的肌张力增加，并且与全面的物理治疗方案相结合时可带来永久性改善。本报告记录了在两年时间里成功使用保妥适治疗一名学龄前儿童脑瘫继发性痉挛的情况。保妥适与特定的物理治疗方案联合使用，以实现独立行走的功能目标。
