Nevretdinova Z, Solovenchuk L, Lapinski A
Institute of Biological Problems of the North, Magadan, Russia.
Arctic Med Res. 1992 Oct;51(4):196-204.
The increased blood levels of thyroid hormones as well as morphologic signs of high activity of thyroid gland were observed in arctic ground squirrel during hibernation. High thyroid activity could explain the characteristics of lipid metabolism observed in the studied species during hibernation-increased lipid unsaturation and decreased cholesterol/phospholipids molar ratio in plasma membranes. High blood concentrations of total lipids, cholesterol, and phospholipids in dormant animals is explained by the dissociation between thermogenic and lipotropic actions of thyroid hormones. We postulate that thyroid hormones participate in long-term regulation of body energy metabolism and of homeoviscous adaptation of membranes during hibernation.
在北极地松鼠冬眠期间,观察到其血液中甲状腺激素水平升高以及甲状腺高活性的形态学迹象。甲状腺高活性可以解释在研究物种冬眠期间观察到的脂质代谢特征——质膜中脂质不饱和度增加和胆固醇/磷脂摩尔比降低。冬眠动物血液中总脂质、胆固醇和磷脂的高浓度是由甲状腺激素的产热作用和促脂作用之间的分离所解释的。我们推测,甲状腺激素参与了冬眠期间身体能量代谢的长期调节以及膜的同黏适应性调节。