Daramola Olaniyi O M, Ogunbiyi Adebola O, George Adekunle O
Dermatology Division, Department of Medicine, University College Hospital, Ibadan, Nigeria.
Int J Dermatol. 2003 Dec;42(12):933-5. doi: 10.1111/j.1365-4632.2003.01715.x.
The presentation of oral lichen planus in anti-hepatitis C virus (HCV) seropositive and seronegative patients was previously evaluated, and the keratotic form of oral lichen planus was found to be more prevalent in anti-HCV seropositive patients. This study evaluated the presentation of cutaneous lichen planus in anti-HCV seropositive and seronegative Nigerians.
Fifty-seven Nigerians with cutaneous lichen planus were carefully examined to determine the form of lichen planus present. All were screened for the presence of anti-HCV by second-generation enzyme-linked immunosorbent assay (ELISA) and grouped as anti-HCV seropositive or anti-HCV seronegative patients.
Nine patients were anti-HCV positive. Seven of these seropositive patients had hypertrophic lichen planus.
Hypertrophic lichen planus in Nigerians is more prevalent with HCV infection.
先前已对丙型肝炎病毒（HCV）血清阳性和血清阴性患者的口腔扁平苔藓表现进行了评估，发现口腔扁平苔藓的角化型在抗HCV血清阳性患者中更为普遍。本研究评估了抗HCV血清阳性和血清阴性尼日利亚人皮肤扁平苔藓的表现。
对57名患有皮肤扁平苔藓的尼日利亚人进行仔细检查，以确定所呈现的扁平苔藓形式。通过第二代酶联免疫吸附测定（ELISA）对所有患者进行抗HCV筛查，并分为抗HCV血清阳性或抗HCV血清阴性患者。
9名患者抗HCV呈阳性。这些血清阳性患者中有7名患有肥厚性扁平苔藓。
在尼日利亚人中，肥厚性扁平苔藓在HCV感染中更为普遍。
