Bach J F
Immunologie Clinique, Hôpital Necker, Paris.
Bull Acad Natl Med. 1992 Jun;176(6):867-71; discussion 871-2.
Cancer immunotherapy is based on the idea that anti-tumor immunity in its various aspects can usefully complement the effect of conventional treatments (surgery, chemotherapy, radiotherapy). Immunotherapy can be active when one stimulates the function of cells capable to contribute to tumor regression, notably by using interleukin-2 or immunomodulators. It can be adoptive when patients' lymphocytes are collected and incubated in vitro in the presence of cytokines to enhance their function and reinjected in the patients. It can be passive when one administers anti-tumor monoclonal antibodies.
癌症免疫疗法基于这样一种理念，即抗肿瘤免疫在各个方面都可以有效地补充传统治疗（手术、化疗、放疗）的效果。当通过使用白细胞介素-2或免疫调节剂刺激能够促进肿瘤消退的细胞功能时，免疫疗法可以是主动的。当收集患者的淋巴细胞并在细胞因子存在的情况下在体外进行培养以增强其功能，然后再重新注入患者体内时，免疫疗法可以是过继性的。当给予抗肿瘤单克隆抗体时，免疫疗法可以是被动的。
