Iinuma M, Tanaka T, Mizuno M, Yamamoto H, Kobayashi Y, Yonemori S
Department of Pharmacognosy, Gifu Pharmaceutical University, Japan.
Chem Pharm Bull (Tokyo). 1992 Oct;40(10):2749-52. doi: 10.1248/cpb.40.2749.
Five flavonoid compounds, including two new isoflavanones, were isolated from the root bark of Erythrina x bidwilli. Their structures were determined to be 2,10-di(gamma,gamma-dimethylallyl)-3,9-dihydroxypterocarpan (erythrabyssin II), 6,8-di(gamma,gamma-dimethylallyl)-7,2',4'-trihydroxyisoflavanone (bidwillon A), 8-gamma,gamma-dimethylallyl-2',4'-dihydroxy-[6",6"-di-methylpyrano - (2",3":7,6)]isoflavanone (bidwillon B), 8-gamma,gamma-dimethylallyl-7,4'-dihydroxyisoflavone (8-gamma,gamma-dimethyl-allyldaidzein), and 8-gamma,gamma-dimethylallyl-5,2',4'-trihydroxy-[6",6"-dimethylpyrano+ ++- (2",3":7,6)]isoflavone (auriculatin), by means of spectroscopic analysis. Some potent activities against oral microbial organisms (Fusobacterium nucleatum and Prevotella intermedia) were shown in these flavonoid compounds.
从刺桐（Erythrina x bidwilli）的根皮中分离出5种黄酮类化合物，包括2种新异黄烷酮。通过光谱分析确定它们的结构分别为2,10-二（γ,γ-二甲基烯丙基）-3,9-二羟基紫檀烷（刺桐素II）、6,8-二（γ,γ-二甲基烯丙基）-7,2',4'-三羟基异黄烷酮（比德维隆A）、8-γ,γ-二甲基烯丙基-2',4'-二羟基-[6",6"-二甲基吡喃并-(2",3":7,6)]异黄烷酮（比德维隆B）、8-γ,γ-二甲基烯丙基-7,4'-二羟基异黄酮（8-γ,γ-二甲基烯丙基黄豆苷元）以及8-γ,γ-二甲基烯丙基-5,2',4'-三羟基-[6",6"-二甲基吡喃并-(2",3":7,6)]异黄酮（耳形草素）。这些黄酮类化合物对口腔微生物（具核梭杆菌和中间普氏菌）显示出一些强效活性。
