Avery Natalie J, King Rosemary M, Knight Susan, Hourihane Jonathan O'B
Division of Infection Inflammation and Repair, University of Southampton, Southampton, UK.
Pediatr Allergy Immunol. 2003 Oct;14(5):378-82. doi: 10.1034/j.1399-3038.2003.00072.x.
Children with a peanut allergy (PA) are faced with food and social restrictions due to the potentially life-threatening nature of their disease, for which there is no cure or treatment. This inevitably impacts upon their quality of life (QoL). QoL of 20 children with PA and 20 children with insulin-dependent diabetes mellitus (IDDM) was measured using two disease-specific QoL questionnaires (higher scores correspond to a poorer QoL). One questionnaire was designed by us and the other was adapted from the Vespid Allergy QoL questionnaire. We gave subjects cameras to record how their QoL is affected over a 24-h period. Response rates for both questionnaires were 100%. Mean ages were 9.0 and 10.4 years for PA and IDDM subjects, respectively. Children with a PA reported a poorer quality of life than children with IDDM: mean scores were 54.85 for PA subjects and 46.40 for diabetics (p = 0.004) in questionnaire 1 and 54.30 and 34.50 (p</=0.001) in questionnaire 2. PA children reported more fear of an adverse event and more anxiety about eating, especially when eating away from home. Photographs fell into seven common categories: food, management, environment, away from home, physical activities, restaurant and people. Most photographs related to food and management issues and revealed difficulties for both groups regarding food restrictions. PA subjects felt more threatened by potential hazards within their environment, felt more restricted by their PA regarding physical activities, and worried more about being away from home. However, they felt safe when carrying epinephrine kits and were positive about eating at familiar restaurants. The QoL in children with PA is more impaired than in children with IDDM. Their anxiety may be considered useful in some situations, promoting better adherence to allergen avoidance advice and rescue plans.
患有花生过敏（PA）的儿童因其疾病具有潜在的生命威胁性，且尚无治愈或治疗方法，故而面临饮食和社交限制。这不可避免地会影响他们的生活质量（QoL）。我们使用两份针对特定疾病的生活质量问卷（分数越高表明生活质量越差），对20名患有PA的儿童和20名患有胰岛素依赖型糖尿病（IDDM）的儿童的生活质量进行了测量。一份问卷由我们自行设计，另一份改编自黄蜂过敏生活质量问卷。我们给受试者相机，以记录他们在24小时内的生活质量受到何种影响。两份问卷的回复率均为100%。PA组和IDDM组受试者的平均年龄分别为9.0岁和10.4岁。患有PA的儿童报告的生活质量比患有IDDM的儿童更差：在问卷1中，PA组受试者的平均得分是54.85，糖尿病组为46.40（p = 0.004）；在问卷2中，得分分别为54.30和34.50（p≤0.001）。PA儿童报告称更害怕不良事件，对饮食更焦虑，尤其是在离家外出就餐时。照片分为七个常见类别：食物、管理、环境、离家外出、体育活动、餐厅和人物。大多数照片与食物和管理问题相关，显示出两组在饮食限制方面都存在困难。PA组受试者感觉其所处环境中的潜在危险对他们构成更大威胁，PA对其体育活动的限制更大，并且离家外出时更担心。然而，他们携带肾上腺素急救包时会感到安全，并且对在熟悉的餐厅就餐持积极态度。患有PA的儿童的生活质量比患有IDDM的儿童受损更严重。他们的焦虑在某些情况下可能被认为是有益的，有助于更好地遵守避免接触过敏原的建议和急救计划。
