Tsoumani Marina, Regent Lynne, Warner Amena, Gallop Katy, Patel Ram, Ryan Robert, Vereda Andrea, Acaster Sarah, DunnGalvin Audrey, Byrne Aideen
Division of Infection, Immunity and Respiratory Medicine, School of Biological Sciences, NIHR Manchester Biomedical Research Centre, Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, University of Manchester, Manchester, United Kingdom.
Anaphylaxis Campaign, Farnborough, United Kingdom.
PLoS One. 2022 Feb 7;17(2):e0262851. doi: 10.1371/journal.pone.0262851. eCollection 2022.
The Allergy to Peanuts imPacting Emotions And Life study (APPEAL) explored the psychosocial burden of living with self-reported peanut allergy experienced by children, teenagers, adults and caregivers in the UK and Ireland. A two-stage (quantitative survey and qualitative interview [APPEAL-1]), cross-sectional study of the psychosocial burden of peanut allergy (APPEAL-2) was conducted. Quantitative data were evaluated using descriptive statistics and qualitative data were analysed using MAXQDA software. A conceptual model specific to UK and Ireland was developed using the concepts identified during the analysis. A total of 284 adults in the UK and Ireland completed the APPEAL-1 survey and 42 individuals participated in APPEAL-2. Respondents reported that peanut allergy restricts their choices in various situations, especially with regard to choosing food when eating out (87% moderately or severely restricted), choosing where to eat (82%), special occasions (76%) and when buying food from a shop (71%). Fifty-two percent of survey participants and 40% of interview participants reported being bullied because of PA. Psychological impact of peanut allergy included feeling at least moderate levels of frustration (70%), uncertainty (79%), and stress (71%). The qualitative analysis identified three different types of coping strategies (daily monitoring or vigilance, communication and planning) and four main areas of individuals' lives that are impacted by peanut allergy (social activities, relationships, emotions and work [adults and caregivers only]). The extent of the impact reported varied substantially between participants, with some reporting many negative consequences of living with peanut allergy and others feeling it has minimal impact on their health-related quality of life. This large survey and interview study highlight the psychosocial burden of peanut allergy for adults, teenagers, children and caregivers in the UK and Ireland. The analysis demonstrates the wide variation in level of impact of peanut allergy and the unmet need for those individuals who experience a substantial burden from living with peanut allergy.
花生过敏对情绪和生活的影响研究（APPEAL）探讨了英国和爱尔兰的儿童、青少年、成年人及照料者自述花生过敏所带来的心理社会负担。开展了一项关于花生过敏心理社会负担的两阶段研究（定量调查和定性访谈[APPEAL - 1]，横断面研究[APPEAL - 2]）。定量数据采用描述性统计进行评估，定性数据使用MAXQDA软件进行分析。利用分析过程中确定的概念，构建了一个适用于英国和爱尔兰的概念模型。英国和爱尔兰共有284名成年人完成了APPEAL - 1调查，42人参与了APPEAL - 2。受访者表示，花生过敏在各种情况下都限制了他们的选择，尤其是外出就餐时选择食物（87%受到中度或严重限制）、选择就餐地点（82%）、特殊场合（76%）以及从商店购买食物时（71%）。52%的调查参与者和40%的访谈参与者报告称因花生过敏而受到欺负。花生过敏的心理影响包括至少感到中度的沮丧（70%）、不确定感（79%）和压力（71%）。定性分析确定了三种不同类型的应对策略（日常监测或警惕、沟通和计划）以及花生过敏影响个人生活的四个主要方面（社交活动、人际关系、情绪和工作[仅针对成年人及照料者]）。报告的影响程度在参与者之间差异很大，一些人报告了花生过敏带来的许多负面后果，而另一些人则认为其对与健康相关的生活质量影响极小。这项大规模的调查和访谈研究凸显了英国和爱尔兰成年人、青少年、儿童及照料者花生过敏的心理社会负担。分析表明，花生过敏的影响程度差异很大，对于那些因花生过敏而承受巨大负担的人来说，需求尚未得到满足。
