Navaza Jorge
Laboratoire de Virologie Molèculaire Structurale, 1 Avenue de la Terrasse, Bât. 14B, CNRS-GIF, 91198 Gif-sur-Yvette, France.
J Struct Biol. 2003 Oct-Nov;144(1-2):13-23. doi: 10.1016/j.jsb.2003.09.007.
The problem of reconstructing an isolated particle from its projections, using spherical harmonics to represent the scattering density, is reformulated. A technique that makes explicit and efficient use of the symmetry to describe the angular part of the scattering density is developed in full detail for the particular case of icosahedral symmetry. It provides a very concise method, where the effort is concentrated in the determination of the radial part of the Fourier transform of the particle scattering density. The method allows individual-image model-independent view determination. An illustrative numerical example is given.
利用球谐函数表示散射密度,从其投影重建孤立粒子的问题被重新表述。针对二十面体对称的特殊情况,详细开发了一种能明确且高效地利用对称性来描述散射密度角向部分的技术。它提供了一种非常简洁的方法,其中工作重点集中在确定粒子散射密度傅里叶变换的径向部分。该方法允许进行与单个图像模型无关的视图确定。给出了一个说明性的数值示例。