High incidence of hepatotoxicity of isoniazid treatment for tuberculosis chemoprophylaxis in patients with rheumatoid arthritis treated with methotrexate or sulfasalazine and anti-tumour necrosis factor inhibitors.
作者信息
Vanhoof J, Landewe S, Van Wijngaerden E, Geusens P
出版信息
Ann Rheum Dis. 2003 Dec;62(12):1241-2. doi: 10.1136/ard.2002.004598.
Abstract
摘要
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High incidence of hepatotoxicity of isoniazid treatment for tuberculosis chemoprophylaxis in patients with rheumatoid arthritis treated with methotrexate or sulfasalazine and anti-tumour necrosis factor inhibitors.在接受甲氨蝶呤或柳氮磺胺吡啶以及抗肿瘤坏死因子抑制剂治疗的类风湿关节炎患者中，使用异烟肼进行结核化学预防治疗时肝毒性发生率较高。
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