Murakami Seiichi, Oda Nobuhiro, Futagami Etsurou, Fujimoto Keiji, Jinnai Yuusuke, Katsuragawa Shigehiko, Nakata Hajime, Aoki Takatoshi, Ikeda Satoshi
Department of Radiology, University of Occupational and Environmental Health Hospital.
Nihon Hoshasen Gijutsu Gakkai Zasshi. 2003 Oct;59(10):1285-94. doi: 10.6009/jjrt.kj00000921637.
Quantitative analysis of bone mass is a method mainly used for the diagnosis of osteoporosis. However, there are cases of osteoporosis that cannot be diagnosed by this method alone. This study was performed to develop a new quantitative method for the evaluation of osteoporosis using texture analysis and geometric feature analysis of trabecular bone on lateral calcaneal computed radiographs. Thirty-seven cases including 11 normal and 26 abnormal lateral calcaneal radiographs were examined. The patients' ages ranged from 24 to 89 years (average age, 58.3 years). The root mean square (RMS) variation and first moment of power spectrum of trabecular bone patterns were determined as quantitative measures for texture analysis. In addition, the total area and total length of trabecular bone were obtained from geometric feature analysis. The RMS variations in pixel values, total area, and total length of trabecular bone were decreased as bone atrophy progressed. These three quantitative measures corresponded well to radiologists' subjective evaluations of bone atrophy. Moreover, our results indicated that these three quantitative measures had strong correlations with bone mineral density of the femoral neck. Therefore, we consider the computerized method with texture analysis and geometric feature analysis of lateral calcaneal radiographs to be very useful for radiologists in evaluating osteoporosis.
骨量的定量分析是一种主要用于诊断骨质疏松症的方法。然而，存在仅通过这种方法无法诊断的骨质疏松症病例。本研究旨在利用跟骨外侧计算机X线片上小梁骨的纹理分析和几何特征分析，开发一种评估骨质疏松症的新定量方法。对包括11例正常和26例异常跟骨外侧X线片在内的37例病例进行了检查。患者年龄范围为24至89岁（平均年龄58.3岁）。确定小梁骨模式的均方根（RMS）变化和功率谱的一阶矩作为纹理分析的定量指标。此外，从小梁骨的几何特征分析中获得其总面积和总长度。随着骨萎缩的进展，小梁骨像素值的RMS变化、总面积和总长度均降低。这三个定量指标与放射科医生对骨萎缩的主观评估高度相符。此外，我们的结果表明，这三个定量指标与股骨颈骨密度密切相关。因此，我们认为对跟骨外侧X线片进行纹理分析和几何特征分析的计算机化方法对放射科医生评估骨质疏松症非常有用。
