Jamal Awatif, Al-Maghrabi Jaudah A
Department of Pathology, Faculty of Medicine, King Abdul-Aziz University Hospital, Jeddah, Kingdom of Saudi Arabia.
Saudi Med J. 2003 Nov;24(11):1225-9.
Cervical carcinoma is an important women's health problem in the Western countries. There are only few published data on this disease in the Kingdom of Saudi Arabia (KSA). The aim of this study is to evaluate the abnormal cytological entities detected by cervical Pap smear in Western region of KSA and to discuss the importance of Pap smears screening programs.
Retrospective review of all the cervical smears present at the King Abdul-Aziz University Hospital, Jeddah, KSA from 1984 to 2000. The reports of 22089 smears were retrieved from the file of the pathology department.
There were 368 (1.66%) abnormal Pap smears out of 22089 smears. Out of these 368 abnormal Pap smears there were 62 (16.8%, mean age 37 year) cervical intraepithelial neoplasia grade 1, 45 (12.2%, mean age 38.5) cervical intraepithelial neoplasia grade 2, 27 (7.3%, mean age 40.5) cervical intraepithelial neoplasia grade 3, 22 (6%, mean age 38.5) positive for malignant cells, 36 (9.8%, mean age 40.5) atypical endocervical cells, 88 (23.9%, mean age 39) atypical squamous cells, 9 (2.4%, mean age 40.5) squamous metaplasia with atypia, 26 (7.1%, mean age 45) squamous cell carcinoma, 6 (1.6%, mean age 36.5) reparative atypia, 2 (5.4% mean age 35) herpes virus changes, 19 (5.1%, mean age 37.5) human papilloma virus changes, 5 (1.4%, mean age 55) adenocarcinoma of endometrium, and 7 (1.9%, men age 43.5) adenocarcinoma of endocervix.
Cervical intraepithelial neoplasia and invasive cervical carcinoma are less common in KSA compared to the Western countries, however, cervical screening programs are necessary nationwide to estimate the actual magnitude of cervical carcinoma and its precursor lesions.
宫颈癌是西方国家重要的女性健康问题。沙特阿拉伯王国（KSA）关于这种疾病的公开数据很少。本研究的目的是评估在KSA西部地区通过宫颈巴氏涂片检测到的异常细胞学实体，并讨论巴氏涂片筛查项目的重要性。
回顾性分析1984年至2000年在沙特阿拉伯吉达阿卜杜勒 - 阿齐兹国王大学医院的所有宫颈涂片。从病理科档案中检索到22089份涂片报告。
在22089份涂片中，有368份（1.66%）巴氏涂片异常。在这368份异常巴氏涂片中，有62份（16.8%，平均年龄37岁）为宫颈上皮内瘤变1级，45份（12.2%，平均年龄38.5岁）为宫颈上皮内瘤变2级，27份（7.3%，平均年龄40.5岁）为宫颈上皮内瘤变3级，22份（6%，平均年龄38.5岁）癌细胞阳性，36份（9.8%，平均年龄40.5岁）为非典型宫颈管细胞，88份（23.9%，平均年龄39岁）为非典型鳞状细胞，9份（2.4%，平均年龄40.5岁）为非典型化生鳞状上皮，26份（7.1%，平均年龄45岁）为鳞状细胞癌，6份（1.6%，平均年龄36.5岁）为修复性非典型，2份（5.4%，平均年龄35岁）为疱疹病毒改变，19份（5.1%，平均年龄37.5岁）为人乳头瘤病毒改变，5份（&1.4%，平均年龄55岁）为子宫内膜腺癌，7份（1.9%，平均年龄43.5岁）为宫颈管腺癌。
与西方国家相比，KSA的宫颈上皮内瘤变和浸润性宫颈癌不太常见，然而，全国范围内有必要开展宫颈筛查项目，以评估宫颈癌及其前驱病变的实际规模。
