Valera E T, Cipolotti R, Bernardes J E, Pacagnella R C, Lima D M, Tone L G, Fonseca B A
Hospital das Clínicas, Universidade de São Paulo (USP), SP, Brazil.
J Pediatr (Rio J). 2000 Jul-Aug;76(4):323-6. doi: 10.2223/jped.3.
To describe the occurrence of transient pancytopenia induced by parvovirus B19 infection in a patient with hereditary hemolytic anemia and to discuss the importance of the diagnosis of this pathology.METHODS: Case report of a child whose diagnosis was made by polymerase chain reaction (PCR) and serology, and review of the literature.CLINICAL REPORT: A twelve year-old male patient with hereditary spherocytosis, presenting non-specific symptoms of an infectious syndrome followed by severe and transient pancytopenia, whose diagnosis was a parvovirus B19 infection.CONCLUSION: The diagnosis of parvovirus infection has a particular importance in hematology, especially on some morbid conditions, among them the hereditary hemolytic anemias. PCR is useful because of its rapidness and sensitivity on the specific diagnosis of this disease.
描述细小病毒B19感染在一名遗传性溶血性贫血患者中诱发的短暂全血细胞减少症的发生情况,并探讨该病症诊断的重要性。方法:对一名通过聚合酶链反应(PCR)和血清学确诊的儿童进行病例报告,并对文献进行综述。临床报告:一名12岁患有遗传性球形红细胞增多症的男性患者,出现感染综合征的非特异性症状,随后出现严重且短暂的全血细胞减少症,其诊断为细小病毒B19感染。结论:细小病毒感染的诊断在血液学中具有特殊重要性,尤其是在某些病态情况下,其中包括遗传性溶血性贫血。PCR因其对该疾病的快速和特异性诊断的敏感性而有用。