Zouaoui A, Maillard J C, Dormont D, Chiras J, Marsault C
Département de Neuroradiologie, Hôpital La Pitié-Salpêtrière, Paris.
J Neuroradiol. 1992 Dec;19(4):271-84.
Nine patients with neurological manifestations of sarcoidosis were explored by MRI and, in some cases, CT. The MRI examinations were performed in T1- and T2-weighted spin-echo sequences in all patients, with gadolinium injection in seven. Several non-specific lesions were demonstrated, the most frequent of them showing on T2-weighted sequences as high-intensity signals in the periventricular white matter and the semi-oval centres. Other abnormalities, such as infiltrations of the hypothalamo-pituitary region, granulomatous masses within the brain tissue and meningeal infiltrations, were observed. These findings were in agreement with those found in the literature. Gadolinium injection seems to be important in this pathology, as it demonstrates lesions that are not visible on conventional T1- and T2-weighted spin-echo sequences.
对9例有结节病神经表现的患者进行了MRI检查,部分患者还进行了CT检查。所有患者均采用T1加权和T2加权自旋回波序列进行MRI检查,7例患者进行了钆增强扫描。发现了几种非特异性病变,其中最常见的在T2加权序列上表现为脑室周围白质和半卵圆中心的高强度信号。还观察到其他异常,如下丘脑-垂体区域浸润、脑组织内肉芽肿性肿块和脑膜浸润。这些发现与文献报道一致。钆增强扫描在这种疾病中似乎很重要,因为它能显示在传统T1加权和T2加权自旋回波序列上不可见的病变。