Ellozy Sharif H, Carroccio Alfio
Department of Surgery, Mount Sinai School of Medicine, One East 100th Street, New York, NY 10029, USA.
Mt Sinai J Med. 2003 Nov;70(6):417-9.
Transcatheter endovascular therapy for peripheral atherosclerotic disease has become more popular. In general, good results have been reported in focal aortoiliac disease. However, the long-term patency of angioplasty in longer, more distal lesions has been less satisfactory. Stenting has not been shown to improve long-term patency compared to angioplasty alone. Drug-eluting stents have shown promise in preventing coronary restenosis, and preliminary results in peripheral arterial disease are encouraging. This review article will discuss the current status of endovascular therapy of aortoiliac and femoropopliteal atherosclerotic disease, the theoretic and experimental basis for the use of drug-eluting stents, and the preliminary results in human studies.
经导管血管内治疗外周动脉粥样硬化疾病已变得更为普遍。总体而言，在局灶性主-髂动脉疾病中已报告有良好疗效。然而，对于更长、更远端病变的血管成形术长期通畅率一直不太令人满意。与单纯血管成形术相比，支架置入术尚未显示能改善长期通畅率。药物洗脱支架已显示出预防冠状动脉再狭窄的前景，在外周动脉疾病中的初步结果也令人鼓舞。这篇综述文章将讨论主-髂动脉和股-腘动脉粥样硬化疾病的血管内治疗现状、使用药物洗脱支架的理论和实验基础以及人体研究的初步结果。
