Turner Barbara J, Laine Christine, Yang Chuya P, Hauck Walter W
Division of General Internal Medicine, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.
Clin Infect Dis. 2003 Dec 15;37 Suppl 5:S457-63. doi: 10.1086/377558.
We examined the effect of drug treatment in 1996 on repeated (> or =2) emergency department visits and hospitalization in 1997 in a cohort of New York State Medicaid-enrolled human immunodeficiency virus (HIV)-positive and HIV-negative drug users. In HIV-positive drug users, the adjusted odds of repeated emergency department visits were increased for those receiving no long-term treatment (odds ratio [OR], 1.65; 95% confidence interval [CI], 1.04-2.75), whereas the adjusted odds for those receiving methadone treatment and those receiving drug-free treatment for > or =6 months did not differ. The adjusted odds of hospitalization in the HIV-positive group were higher for those receiving long-term methadone treatment (OR, 1.69; 95% CI, 1.14-2.55) and for those receiving no long-term treatment (OR, 1.91; 95% CI, 1.29-2.88), compared with those receiving drug-free treatment. In the HIV-negative group, these associations were similar but weaker. For both HIV-positive and HIV-negative drug users, long-term drug-free treatment was at least as effective as long-term methadone treatment in reducing use of services indicative of poorer access to care and/or poorer health.
我们研究了1996年药物治疗对纽约州医疗补助计划参保的一组人类免疫缺陷病毒(HIV)阳性和HIV阴性吸毒者在1997年反复(≥2次)急诊就诊和住院情况的影响。在HIV阳性吸毒者中,未接受长期治疗者反复急诊就诊的校正比值比(OR)升高(OR = 1.65;95%置信区间[CI],1.04 - 2.75),而接受美沙酮治疗者和接受≥6个月戒毒治疗者的校正比值比无差异。与接受戒毒治疗者相比,HIV阳性组中接受长期美沙酮治疗者(OR = 1.69;95% CI,1.14 - 2.55)和未接受长期治疗者(OR = 1.91;95% CI,1.29 - 2.88)住院的校正比值比更高。在HIV阴性组中,这些关联相似但较弱。对于HIV阳性和HIV阴性吸毒者,长期戒毒治疗在减少表明获得医疗服务机会较差和/或健康状况较差的服务使用方面至少与长期美沙酮治疗一样有效。