灼口综合征患者情绪障碍与血清白细胞介素-2及白细胞介素-6的相关性研究
[Correlations among mood disorder, serum interleukin-2 and interleukin-6 in patients with burning mouth syndrome].
作者信息
Xia Juan, Lin Mei, Jin Zaorong
机构信息
Department of Oral Medicine, West China College of Stomatology, Sichuan University, Chengdu 610041, China.
出版信息
Hua Xi Kou Qiang Yi Xue Za Zhi. 2003 Oct;21(5):377-8.
OBJECTIVE
To examine serum IL-2 and IL-6 levels in BMS patients with or without depression and make clear the relationship between serum IL-2, IL-6 and mood disorder.
METHODS
Serum IL-2 and IL-6 were examined in 48 BMS patients by means of ELISA. The Hamilton Depression Rating Scale (HDRS) was used to evaluate the depressive symptomatology.
RESULTS
There was no significant difference in serum IL-2 and IL-6 among BMS patients with or without depression. Mood disorder was not correlated to serum IL-2 and IL-6, but positively correlated to pain levels.
CONCLUSION
Depression status may not influence serum IL-2 and IL-6 levels significantly, but it has a relationship with BMS. The HDRS can be used to determine depression status in BMS patients in order to help clinical treatment.
目的
检测伴有或不伴有抑郁的灼口综合征（BMS）患者血清白细胞介素-2（IL-2）和白细胞介素-6（IL-6）水平，明确血清IL-2、IL-6与情绪障碍之间的关系。
方法
采用酶联免疫吸附测定法（ELISA）检测48例BMS患者血清IL-2和IL-6水平。采用汉密尔顿抑郁量表（HDRS）评估抑郁症状。
结果
伴有或不伴有抑郁的BMS患者血清IL-2和IL-6水平无显著差异。情绪障碍与血清IL-2和IL-6无相关性，但与疼痛程度呈正相关。
结论
抑郁状态可能不会显著影响血清IL-2和IL-6水平，但与BMS有关。HDRS可用于确定BMS患者的抑郁状态，以辅助临床治疗。
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