Selvakannan Pr, Mandal Saikat, Phadtare Sumant, Gole Anand, Pasricha Renu, Adyanthaya S D, Sastry Murali
Materials Chemistry Division, National Chemical Laboratory, Pune 411 008, India.
J Colloid Interface Sci. 2004 Jan 1;269(1):97-102. doi: 10.1016/s0021-9797(03)00616-7.
The synthesis of water-dispersible amino-acid-protected gold nanoparticles by the spontaneous reduction of aqueous chloroaurate ions by tryptophan is described. Water-dispersible gold nanoparticles may also be obtained by the sequential synthesis of the gold nanoparticles by borohydride reduction of chloroauric acid followed by capping with tryptophan. Comparison of the proton NMR spectroscopic signatures from the tryptophan-protected gold nanoparticles obtained by the two processes indicated that the indole group in tryptophan is responsible for reduction of the aqueous chloroaurate ions. The reduction of the metal ions is accompanied by oxidative polymerization of the indole group of the tryptophan molecules and, consequently, some degree of cross-linking of the gold nanoparticles.
本文描述了通过色氨酸将氯金酸盐水溶液中的离子自发还原，合成水分散性氨基酸保护的金纳米颗粒的方法。水分散性金纳米颗粒也可以通过以下步骤获得：先用硼氢化钠还原氯金酸来顺序合成金纳米颗粒，然后用色氨酸进行封端。对通过这两种方法获得的色氨酸保护的金纳米颗粒的质子核磁共振光谱特征进行比较表明，色氨酸中的吲哚基团负责还原氯金酸盐水溶液中的离子。金属离子的还原伴随着色氨酸分子吲哚基团的氧化聚合，因此，金纳米颗粒会有一定程度的交联。
