Odaci Ersan, Sahin Bünyamin, Sonmez Osman Fikret, Kaplan Süleyman, Bas Orhan, Bilgic Sait, Bek Yüksel, Ergür Hayati
Department of Histology and Embryology, Medical School, Ondokuz Mayis University, 55139 Samsun, Turkey.
Eur J Radiol. 2003 Dec;48(3):316-26. doi: 10.1016/s0720-048x(03)00077-9.
The exact volume of the vertebral body is necessary for the evaluation, treatment and surgical application of related vertebral body. Thereby, the volume changes of the vertebral body are monitored, such as infectious diseases of vertebra and traumatic or non-traumatic fractures and deformities of the spine. Several studies have been conducted for the assessment of the vertebral body size based on the evaluation of the different criteria of the spine using different techniques. However, we have not found any detailed study in the literature describing the combination of the Cavalieri principle and vertebral body volume estimation.
In the present study we describe a rapid, simple, accurate and practical technique for estimating the volume of vertebral body. Two specimens were taken from the cadavers including ten lumbar vertebras and were scanned in axial, sagittal and coronal section planes by a computed tomography (CT) machine. The consecutive sections in 5 and 3 mm thicknesses were used to estimate the total volume of the vertebral bodies by means of the Cavalieri principle. Furthermore, to evaluate inter-observer differences the volume estimations were carried out by three performers.
There were no significant differences between the performers' estimates and real volumes of the vertebral bodies (P>0.05) and also between the performers' volume estimates (P>0.05). The section thickness and the section plains did not affect the accuracy of the estimates (P>0.05). A high correlation was seen between the estimates of performers and the real volumes of the vertebral bodies (r=0.881).
We concluded that the combination of CT scanning with the Cavalieri principle is a direct and accurate technique that can be safely applied to estimate the volume of the vertebral body with the mean of 5 min and 11 s workload per vertebra.
相关椎体的评估、治疗及手术应用需要精确的椎体体积。因此，需监测椎体的体积变化，如椎体感染性疾病、脊柱创伤性或非创伤性骨折及畸形。基于不同技术对脊柱不同标准的评估，已有多项研究用于评估椎体大小。然而，我们在文献中未发现任何详细研究描述卡瓦列里原理与椎体体积估计的结合。
在本研究中，我们描述了一种快速、简单、准确且实用的椎体体积估计技术。从尸体上获取两个包含十个腰椎椎体的标本，并用计算机断层扫描（CT）机在轴向、矢状和冠状截面平面进行扫描。采用5毫米和3毫米厚度的连续切片，借助卡瓦列里原理估计椎体总体积。此外，为评估观察者间差异，由三名操作者进行体积估计。
操作者对椎体的估计值与实际体积之间（P>0.05）以及操作者之间的体积估计值之间（P>0.05）均无显著差异。切片厚度和切片平面不影响估计的准确性（P>0.05）。操作者的估计值与椎体实际体积之间存在高度相关性（r = 0.881）。
我们得出结论，CT扫描与卡瓦列里原理相结合是一种直接且准确的技术，可安全用于估计椎体体积，每个椎体平均工作量为5分11秒。
