Brosseau Olivier E F, Mahdjoub Rachid, Seurin Marie José, Thiriet Patrice, Gozal David, Briguet André
UMR 5012 CNRS, Domaine Scientifique de la Doua, CPE, 3, rue Victor-Grignard, 69616 Villeurbanne, France.
Biochimie. 2003 Sep;85(9):885-90. doi: 10.1016/s0300-9084(03)00125-1.
Potential differences were assessed between the dominant (D) and non-dominant (ND) forearms of sedentary subjects during anaerobic exercise. Subjects performed voluntary concentric contractions of D and ND forearm muscle during a series of three high-intensity (60% of the maximal voluntary contraction force (MVC)) exercise bouts. The time-dependent changes in intracellular pH (pH(i)), Pi, and PCr concentrations, and their relation to muscular work were examined using 31P magnetic resonance spectroscopy (MRS) techniques, and revealed that D forearm metabolic kinetics in sedentary individuals are improved during repetitive high-intensity exercise compared to their respective ND forearm muscle. We postulate that the more regular and preferential utilization of the D limb leads to a "trained-like" condition.