Chernin V V, Fomina L A
Tver State Medical Academy.
Eksp Klin Gastroenterol. 2003(4):44-8, 114.
Examination of 150 ulcer patients determined that the exacerbation of the disease proceeds against the background of essential augmentation of calcium in the blood, which is most expressed at the acute phase of relapse, at the localization of ulcer in the duodenum, in men of young age. This is accompanied by the rising production of hydrochloric acid and pepsinogen, decrease of production of gastromucoproteins, hypermotor dyskinesia of stomach, hypocoagulation, infringement of microcirculation in the mucous coat of the gastroduodenal zone displayed as microthromboses, plasmorrhagias, hemorrhages. The inclusion of the calcium antagonist Corinfarum in the complex therapy reliably accelerates the liquidation of signs of relapse, reduces terms, increases the percentage of ulcer cicatrisation, and promotes normalization of stomach functions, calcium balance, hemostasis and microcirculation.
对150名溃疡患者的检查确定，疾病的加剧是在血液中钙显著增加的背景下发生的，这在复发急性期、十二指肠溃疡定位时以及年轻男性中表现最为明显。这伴随着盐酸和胃蛋白酶原分泌增加、胃粘蛋白分泌减少、胃运动亢进性运动障碍、低凝、胃十二指肠区粘膜层微循环障碍，表现为微血栓形成、血浆渗出、出血。在综合治疗中加入钙拮抗剂科里法鲁姆可可靠地加速复发症状的消除，缩短病程，提高溃疡愈合率，并促进胃功能、钙平衡、止血和微循环的正常化。
