Muise Aleixo, Tallett Susan E, Silverman Earl D
Department of Paediatrics, University of Toronto, Hospital for Sick Children, Toronto, Ontario, Canada M5G 1X8.
Pediatrics. 2003 Dec;112(6 Pt 1):e495. doi: 10.1542/peds.112.6.e495.
Kawasaki disease (KD) patients are known to be at increased risk for coronary artery lesions. We present evidence of another possible complication associated with KD: macrophage activation syndrome (MAS). In this case, a patient with KD and prolonged fever developed MAS. This case is of particular interest because of the late age of onset and recurrent nature of KD as well as the complication of MAS. We also present a review of the literature that supports the inclusion of MAS as an infrequent complication of KD.
已知川崎病(KD)患者发生冠状动脉病变的风险增加。我们提供了与KD相关的另一种可能并发症的证据:巨噬细胞活化综合征(MAS)。在本病例中,一名患有KD且持续发热的患者发生了MAS。由于KD发病年龄较晚且具有复发性以及出现了MAS并发症,该病例特别引人关注。我们还对文献进行了综述,支持将MAS列为KD的一种罕见并发症。