Shiba Masahiro, Fujii Takahiro, Takatera Hiroshi
Department of Urology, Yao Tokusyukai General Hospital.
Hinyokika Kiyo. 2003 Oct;49(10):599-601.
A 56-year-old man who had previously undergone transurethral resection and intra-arterial chemotherapy for bladder cancer developed irritable bladder, bilateral conjunctivitis and arthritis including the knees, ankles and sacroiliac joints after starting intravesical Calmette-Guerin bacillus (BCG) immunotherapy. These symptoms were in agreement with the features of Reiter syndrome. One month after cessation of the intravesical BCG immunotherapy and initiation of the treatment with a non-steroidal anti-inflammatory drug (NSAID), he was not complaining of symptoms. Reiter syndrome is an uncommon complication after intravesical BCG immunotherapy. Nevertheless, since the prolonged arthritis has a possibility to cause joint deformity, we must pay serious attention to this side effect.
一名56岁男性,此前因膀胱癌接受过经尿道切除术和动脉内化疗,在开始膀胱内卡介苗(BCG)免疫治疗后出现膀胱刺激征、双侧结膜炎以及包括膝关节、踝关节和骶髂关节在内的关节炎。这些症状与赖特综合征的特征相符。在停止膀胱内BCG免疫治疗并开始使用非甾体抗炎药(NSAID)治疗1个月后,他没有症状主诉。赖特综合征是膀胱内BCG免疫治疗后一种罕见的并发症。然而,由于长期关节炎有可能导致关节畸形,我们必须认真关注这种副作用。