Macía Villa Cristina, Sifuentes Giraldo Walter, Boteanu Alina, González Lanza Mariano, Bachiller Corral Javier
Servicio de Reumatología, Hospital Universitario Ramón y Cajal, Madrid, Spain.
Reumatol Clin. 2012 Sep-Oct;8(5):284-6. doi: 10.1016/j.reuma.2011.11.009. Epub 2012 Feb 28.
The intravesical instilation of bacillus Calmette-Guérin (BCG) is a widely used and efficacious procedure for treatment of intermediate to high-grade superficial bladder cancer. The occurrence of osteoarticular side effects is infrequent compared to the number of administrated doses, and reactive arthritis is included within these effects. We present the case of a 54 years old HLA-27 (+) male, who developed reactive arthritis featuring asymmetric olygoarthritis and dactylitis after the second intravesical BCG instillation, which was resolved with administration of Etoricoxib and Isoniazid.
膀胱内灌注卡介苗（BCG）是治疗中高级别浅表性膀胱癌广泛应用且有效的方法。与给药剂量相比，骨关节炎副作用的发生率较低，反应性关节炎也包含在这些副作用之中。我们报告一例54岁HLA - 27（+）男性患者，在第二次膀胱内灌注BCG后出现以不对称寡关节炎和指（趾）炎为特征的反应性关节炎，通过服用依托考昔和异烟肼后病情得到缓解。
