Kuijper E J, Wiggerts H O, Jonker G J, Schaal K P, de Gans J
Department of Bacteriology, Academic Medical Centre, Amsterdam, The Netherlands.
Scand J Infect Dis. 1992;24(5):667-72. doi: 10.3109/00365549209054655.
A 44-year-old man presented with pulmonary lesions and neurological symptoms suggestive of lung carcinoma with cerebral metastases. He had non-specific chest X-ray findings since 6 years and he also suffered from relapsing purulent skin lesions which resolved spontaneously or by short courses of antibiotic treatment. When corticosteroids were given, multiple subcutaneous swellings developed that spontaneously ruptured. The pus contained Actinomyces meyeri and Actinobacillus actinomycetemcomitans. On operation, the intracerebral lesions appeared to be abscesses and the same bacteria were cultured as from the skin lesions. Bronchoscopical examination did not reveal a diagnosis. Amoxicillin was given for 12 months and the patient recovered.
一名44岁男性因肺部病变及提示肺癌伴脑转移的神经症状就诊。6年来他胸部X线检查结果无特异性,还患有复发性化脓性皮肤病变,这些病变可自行消退或经短期抗生素治疗后消退。使用皮质类固醇时,出现多个皮下肿胀并自行破溃。脓液中含有迈氏放线菌和伴放线放线杆菌。手术时,脑内病变似乎为脓肿,培养出的细菌与皮肤病变中的相同。支气管镜检查未明确诊断。给予阿莫西林治疗12个月后,患者康复。