电能为旋转式ATP合酶提供能量。

Electrical power fuels rotary ATP synthase.

作者信息

Dimroth Peter, von Ballmoos Christoph, Meier Thomas, Kaim Georg

机构信息

Institut für Mikrobiologie der Eidgenössischen Technischen Hochschule, ETH Zentrum, CH-8092 Zürich, Switzerland.

出版信息

Structure. 2003 Dec;11(12):1469-73. doi: 10.1016/j.str.2003.11.011.

DOI:10.1016/j.str.2003.11.011

PMID:14656431

Abstract

ATP synthesis by F-type ATP synthases consumes energy stored in a transmembrane electrochemical gradient of protons or sodium ions. The electric component of the ion motive force is crucial for ATP synthesis. Here, we incorporate recent results on structure and function of the F(0) domain and present a mechanism for torque generation with the fundamental nature of the membrane potential as driving force in the core.

摘要

F型ATP合酶合成ATP消耗储存在质子或钠离子跨膜电化学梯度中的能量。离子驱动力的电学成分对于ATP合成至关重要。在此，我们纳入了关于F(0)结构域结构和功能的最新研究结果，并提出了一种以膜电位的基本性质为核心驱动力产生扭矩的机制。