Ilić S
Institute of Cardiovascular Diseases, Niska Banja.
Srp Arh Celok Lek. 1992 Mar-Apr;120(3-4):115-9.
Patients after myocardial infarction have a high incidence of both frequent and complex ventricular arrhythmias. Arrhythmias detected by 24-hour electrocardiographic recordings at hospital discharge are predictive of next cardiac mortality. Both left ventricular dysfunction and ventricular arrhythmias have been associated with poor prognosis following acute myocardial infarction. But dysfunction of the left ventricle and ventricular arrhythmias are independently related to mortality. This finding provides a rationale for treating patients with frequent and/or complex ventricular arrhythmias detected at hospital discharge after acute myocardial infarction. Beta-blockers should be considered as antiarrhythmic drugs of choice in the treatment of postinfarction patients with ventricular arrhythmias in order to reduce both ventricular arrhythmias and cardiac mortality.
心肌梗死后的患者频发和复杂性室性心律失常的发生率很高。出院时通过24小时心电图记录检测到的心律失常可预测下次心脏死亡。左心室功能障碍和室性心律失常均与急性心肌梗死后的不良预后相关。但左心室功能障碍和室性心律失常与死亡率独立相关。这一发现为治疗急性心肌梗死后出院时检测到频发和/或复杂性室性心律失常的患者提供了理论依据。为了减少室性心律失常和心脏死亡率，β受体阻滞剂应被视为治疗心肌梗死后室性心律失常患者的首选抗心律失常药物。
