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[福寿螺神经元θ波后胆碱敏感增强的体液因子依赖性]

[Humoral factor dependence of neuronal post-theta choline-sensitive potentiation in Helix Lucorum].

作者信息

Abramova M S, Drozdova E I, Nistratova V L, Pivovarov A S

机构信息

Department of Higher Nervous Activity, Lomonosov State University, Moscow.

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 2003 Sep-Oct;53(5):533-6.

Abstract

Comparison of posttetanic changes of the acetylcholine-induced inward current (ACh-current) in command Helix lucorum neurones at different conditions (using stop flow of saline through the chamber with a ganglia preparation and using flow of saline) was made. Flow of saline reduces latency and degree of posttetanic increase of the ACh-current in neurones. Earlier and weak posttetanic potentiation of the ACh-current in command Helix lucorum neurones during flow of saline through the chamber with a ganglia preparation testifies to participation of the humoral factor in the mechanism of posttetanic potentiation of cholinosensitivity of somatic membrane in postsynaptic neurone.

摘要

对不同条件下(通过停止含神经节标本的腔室内生理盐水流动以及使用生理盐水流动)皱襞盘绕螺指令神经元中乙酰胆碱诱导的内向电流(ACh电流)的强直后变化进行了比较。生理盐水流动可缩短神经元中ACh电流强直后增加的潜伏期并降低其程度。在含神经节标本的腔室内有生理盐水流动时,皱襞盘绕螺指令神经元中ACh电流更早且更弱的强直后增强证明了体液因子参与了突触后神经元中体膜胆碱敏感性强直后增强机制。

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