Papaioannou D S, Kyriakis C S, Alexopoulos C, Tzika E D, Polizopoulou Z S, Kyriakis S C
Clinic of Productive Animal Medicine, School of Veterinary Medicine, Aristotle University of Thessaloniki, 540 06 Thessaloniki, Macedonia, Greece.
Res Vet Sci. 2004 Feb;76(1):19-29. doi: 10.1016/j.rvsc.2003.08.006.
This study was conducted to assess the effect of dietary use of a clinoptilolite-rich tuff (Cp) on health status and performance of weaned, growing and finishing pigs and its compatibility during simultaneous oral administration of antimicrobials (AM) such as enrofloxacin (E) or salinomycin (S). Weaners (720) were assigned in 2 experimental groups and 4 subgroups based on the inclusion or not of Cp and AM in their feed (subgroups: NC, ES, Cp, Cp+ES) in order to evaluate their health status, under PWDS prevailing herd conditions. A second part of the trial aimed to the evaluation of piglet performance under conditions with minimized PWDS herd risks. For this purpose, a second set of 264 weaners were assigned in 2 groups and 4 subgroups, in a respective manner. All piglets remained on-trial until slaughtering age; Cp was incorporated in their feed at a rate of 2% from the day of weaning until slaughtering. The health status evaluation consisted in monitoring piglets for adverse effects related to Cp consumption, average daily diarrhoea scoring during weaning and mortality rate calculations throughout. Performance evaluation included individual weighing at the end of weaning, growing and fattening periods and feed consumption assessments. Average daily gain (ADG), average daily feed intake (ADFI) and feed conversion ration (FCR) on a pen basis were further calculated. Cp ingestion was well tolerated by the piglets. Simultaneous administration of Cp and AM in feed, resulted in less severe forms of PWDS, which had a shorter clinical course (P<0.05). Mortality decreased (P<0.05) during the weaning period due to AM administration. Concerning mean pig body weight at the end of each production phase, both Cp and AM had favorable effects (P<0.05). ADG estimated for the whole observation period was improved (P<0.05) by Cp-use along with AM. FCR improvements (P<0.05) were noticed during the different stages of growth due to AM or Cp administration, while Cp/AM interaction was noticed only at weaning (P<0.05).
本研究旨在评估日粮中使用富含斜发沸石的凝灰岩(Cp)对断奶仔猪、生长猪和育肥猪健康状况及生产性能的影响,以及在同时口服恩诺沙星(E)或盐霉素(S)等抗菌药物(AM)期间其兼容性。720头断奶仔猪根据饲料中是否添加Cp和AM被分为2个实验组和4个亚组(亚组:NC、ES、Cp、Cp + ES),以便在猪瘟腹泻综合征(PWDS)流行的猪群条件下评估其健康状况。试验的第二部分旨在评估在PWDS猪群风险最小化的条件下仔猪的生产性能。为此,另外264头断奶仔猪以相应方式分为2组和4个亚组。所有仔猪一直试验到屠宰年龄;从断奶之日起至屠宰,Cp以2%的比例添加到它们的饲料中。健康状况评估包括监测仔猪与食用Cp相关的不良反应、断奶期间的平均每日腹泻评分以及全程死亡率计算。生产性能评估包括断奶、生长和育肥期结束时的个体称重以及采食量评估。进一步计算栏内基础上的平均日增重(ADG)、平均日采食量(ADFI)和饲料转化率(FCR)。仔猪对摄入Cp耐受性良好。饲料中同时添加Cp和AM,导致PWDS症状较轻,临床病程较短(P<0.05)。由于使用AM,断奶期间死亡率降低(P<0.05)。关于每个生产阶段结束时猪的平均体重,Cp和AM均有良好效果(P<0.05)。整个观察期内,同时使用Cp和AM提高了ADG(P<0.05)。由于使用AM或Cp,在不同生长阶段FCR有所改善(P<0.05),而Cp/AM相互作用仅在断奶时出现(P<0.05)。