Wu Yan-Qi, Li Ya, Lin Xian-Feng, Liu Zhong-Li, Li Yu
National Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, PR China.
Pharmazie. 2003 Nov;58(11):833-5.
From the ethanolic extract of the whole plant of Anaphalis aureo-punctata, a new acylated flavonoid glycoside 3-O-kaempferol-3-O-acetyl-6-O-(p-coumaroyl)-beta-D-glucopyranoside (1), and five known phenolic compounds were isolated. Their structures were established by spectral methods (UV, IR, MS, 1D, 2D-NMR). The flavonoid glycosides, 1, 2 and 3 showed markedly inhibited oxidative DNA strand breaks induced by Fenton reaction and NADH/PMS in a concentration-dependent manner.
从金腺香青全草的乙醇提取物中，分离得到一种新的酰化黄酮糖苷3 - O - 山奈酚 - 3 - O - 乙酰基 - 6 - O -（对香豆酰基）-β - D - 吡喃葡萄糖苷（1）和五种已知的酚类化合物。通过光谱方法（紫外、红外、质谱、一维、二维核磁共振）确定了它们的结构。黄酮糖苷1、2和3以浓度依赖的方式显著抑制了由芬顿反应和NADH/PMS诱导的氧化性DNA链断裂。
