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良性腹膜后神经鞘瘤:病例系列及文献综述

Benign retroperitoneal schwannoma: a case series and review of the literature.

作者信息

Daneshmand Siamak, Youssefzadeh David, Chamie Karim, Boswell William, Wu Nancy, Stein John P, Boyd Stuart, Skinner Donald G

机构信息

Department of Urology, University of Southern California Keck School of Medicine, Los Angeles, California, USA.

出版信息

Urology. 2003 Dec;62(6):993-7. doi: 10.1016/s0090-4295(03)00792-1.

Abstract

OBJECTIVES

To present our experience with four retroperitoneal schwannomas treated by surgical excision and review the current literature. Retroperitoneal schwannomas are rare, benign tumors and infrequently present to the urologist.

METHODS

From 1997 through 2002, the charts of 164 patients with a diagnosis of benign retroperitoneal soft tissue mass were reviewed. Of those, four had a pathologic diagnosis of retroperitoneal schwannoma.

RESULTS

Three of the 4 patients were women, with a median age of 54 years (range 46 to 80). The average tumor size was 13.7 cm (range 8.8 to 20). All patients underwent magnetic resonance imaging, computed tomography, or ultrasonography, and 3 of the 4 patients underwent a computed tomography-guided fine needle aspiration biopsy (all were either inaccurate or inconclusive). All patients underwent complete tumor excision with free margins of resection and tolerated surgery without any complications. None of the patients have had any evidence of recurrence at a mean follow-up of 26 months (range 10 to 48).

CONCLUSIONS

Retroperitoneal schwannomas are difficult to diagnose preoperatively. Computed tomography-guided fine needle aspiration biopsy does not appear to provide an accurate preoperative diagnosis. The surgical approach should focus on complete excision of the mass. Patients undergoing complete surgical resection tend to do well without evidence of early recurrence.

摘要

目的

介绍我们对4例经手术切除的腹膜后神经鞘瘤的治疗经验,并回顾当前文献。腹膜后神经鞘瘤是罕见的良性肿瘤,很少出现在泌尿外科医生面前。

方法

回顾1997年至2002年期间164例诊断为良性腹膜后软组织肿块患者的病历。其中,4例经病理诊断为腹膜后神经鞘瘤。

结果

4例患者中有3例为女性,中位年龄54岁(范围46至80岁)。肿瘤平均大小为13.7 cm(范围8.8至20 cm)。所有患者均接受了磁共振成像、计算机断层扫描或超声检查,4例患者中有3例接受了计算机断层扫描引导下的细针穿刺活检(结果均不准确或无定论)。所有患者均接受了肿瘤完整切除,切缘阴性,手术耐受性良好,无任何并发症。平均随访26个月(范围10至48个月),所有患者均无复发迹象。

结论

腹膜后神经鞘瘤术前难以诊断。计算机断层扫描引导下的细针穿刺活检似乎不能提供准确的术前诊断。手术方法应侧重于完整切除肿块。接受完整手术切除的患者往往预后良好,无早期复发迹象。

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