Zaafouri Elmontassar Belleh, Rihane Sarah, Omry Ahmed, Ferjaoui Wael, Haloui Nabil, Rebii Saber
General Surgery Department, Center for Traumatology and Major Burns, 1st of May Street, El Iskan City, 2013, Ben Arous, Tunisia; Faculty of Medicine of Tunis. 15, Djebel Lakhdhar Street, 1007 Bab Saadoun, Tunis, Tunisia.
General Surgery Department, Military Hospital of Tunis, Mont Fleury, 1008, Tunis, Tunisia; Faculty of Medicine of Tunis. 15, Djebel Lakhdhar Street, 1007 Bab Saadoun, Tunis, Tunisia.
Int J Surg Case Rep. 2025 Feb;127:110862. doi: 10.1016/j.ijscr.2025.110862. Epub 2025 Jan 11.
Retroperitoneal schwannomas are extremely rare, benign tumors originating from Schwann cells in peripheral nerve sheaths, with few reported cases. Their deep location and nonspecific symptoms make preoperative diagnosis challenging, often requiring imaging and surgical resection for confirmation. This case highlights an uncommon presentation of retroperitoneal schwannoma in a young patient, emphasizing its rarity.
An 18-year-old male presented with a progressively enlarging, non-tender mass in the left flank. Imaging revealed an 8 × 7 cm well-circumscribed, encapsulated mass displacing adjacent major vessels without invasion. The patient underwent successful surgical resection, and histopathology confirmed a benign schwannoma. Immunohistochemistry showed strong S100 protein positivity, with no signs of malignancy. Follow-up was uneventful, with no recurrence at six months.
Retroperitoneal schwannomas, typically slow-growing and benign, are infrequently encountered. Due to their nonspecific presentation, they often reach considerable size before detection. Imaging may suggest diagnosis but is not definitive, making surgical excision essential for confirmation. Complete resection is generally recommended to reduce recurrence, though partial excision may be appropriate when adjacent critical structures are involved.
Retroperitoneal schwannomas are rare and challenging to diagnose preoperatively. Complete surgical resection remains the primary approach, allowing histological confirmation and reducing recurrence risk. This case underscores the importance of considering retroperitoneal schwannomas in young patients presenting with atypical retroperitoneal masses.
腹膜后神经鞘瘤极为罕见，是起源于周围神经鞘雪旺细胞的良性肿瘤，报道的病例很少。其位置较深且症状不具特异性，使得术前诊断具有挑战性，通常需要影像学检查和手术切除来确诊。本病例突出了一名年轻患者腹膜后神经鞘瘤的罕见表现。
一名18岁男性患者，左侧腰部出现一个逐渐增大的无痛性肿块。影像学检查显示一个8×7厘米边界清晰、有包膜的肿块，推移相邻大血管但未侵犯。患者接受了成功的手术切除，组织病理学证实为良性神经鞘瘤。免疫组织化学显示S100蛋白强阳性，无恶性迹象。随访情况良好，六个月时无复发。
腹膜后神经鞘瘤通常生长缓慢且为良性，很少见。由于其表现不具特异性，常在被发现前已长得相当大。影像学检查可能提示诊断但不明确，因此手术切除对于确诊至关重要。一般建议完整切除以降低复发风险，不过当涉及相邻关键结构时，部分切除可能也是合适的。
腹膜后神经鞘瘤罕见，术前诊断具有挑战性。完整的手术切除仍然是主要方法，可实现组织学确诊并降低复发风险。本病例强调了在出现非典型腹膜后肿块的年轻患者中考虑腹膜后神经鞘瘤的重要性。
