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超声引导下髂腰肌肉毒毒素注射技术

Ultrasound-guided botulinum toxin injection technique for the iliopsoas muscle.

作者信息

Westhoff Bettina, Seller Konrad, Wild Alexander, Jaeger Marcus, Krauspe Ruediger

机构信息

Department of Orthopaedics, Heinrich-Heine University Duesseldorf, Duesseldorf, Germany.

出版信息

Dev Med Child Neurol. 2003 Dec;45(12):829-32. doi: 10.1017/s0012162203001531.

Abstract

Intramuscular botulinum toxin A injections are beneficial for the treatment of functional shortening of the iliopsoas muscle, but it is difficult to achieve precise needle positioning and injection. As a solution to this we present an ultrasound-guided injection technique for the iliopsoas muscle using an anterior approach from the groin. The procedure was performed 26 times in 13 patients (seven males, six females; mean age 11 years, SD 9 years 8 months; age range 4 to 31 years), 10 times bilaterally. Indications were functional iliopsoas shortening due to cerebral palsy (17 hips), hereditary spastic paraplegia (four hips), and Perthes disease (five hips). In all cases the iliopsoas muscle was identified easily by ultrasound; the placement of the injection needle and injection into the site of interest were observed during real time. No complications were encountered. Botulinum toxin A (BTX-A) injections have become established as a standard procedure for the treatment of functional shortening of different muscles in persons with spasticity or dystonia (Kessler et al. 1999, Bakheit et al. 2001, Kirschner et al. 2001). Optimal needle placement is essential to avoid severe side effects and to assess lack of response to the drug or incorrect region of injection. While injection into superficial, very palpable muscles is quite easy, the approach to other muscles such as the iliopsoas muscle may be more difficult and the placement of the needle for an optimal injection site is harder to control. As a solution to this, we present an ultrasound-guided injection technique. The main indications for BTX-A injections in the iliopsoas muscle are dynamic hip flexion deformities mostly due to spastic conditions which may compromise walking (increased anterior pelvic tilt during the whole gait cycle, decreased hip extension at terminal stance, increased peak hip flexion during swing; Molenaers et al. 1999. Another indication might be decentration of the femoral head (as part of an injection programme which also includes other muscles like the adductors and the medial hamstrings) for pain relief, reducing care difficulties and, possibly, prevention of further decentration (Porta 2000, Foster et al. 2001, Deleplanque et al. 2002, Lubik et al. 2002). In Perthes disease, BTX-A injections in the iliopsoas muscle and the adductors may prevent a fixed deformity, which is a negative prognostic factor.

摘要

肌内注射A型肉毒杆菌毒素对治疗髂腰肌功能性缩短有益,但难以实现精确的进针定位和注射。作为解决方案,我们提出一种经腹股沟前路的超声引导下髂腰肌注射技术。该操作在13例患者(7例男性,6例女性;平均年龄11岁,标准差9岁8个月;年龄范围4至31岁)中进行了26次,其中10次为双侧注射。适应证为脑性瘫痪导致的髂腰肌功能性缩短(17髋)、遗传性痉挛性截瘫(4髋)和佩吉特病(5髋)。在所有病例中,均能通过超声轻松识别髂腰肌;实时观察注射针的放置及向目标部位的注射过程。未发生并发症。A型肉毒杆菌毒素(BTX-A)注射已成为治疗痉挛或肌张力障碍患者不同肌肉功能性缩短的标准操作(凯斯勒等人,1999年;巴赫伊特等人,2001年;基施纳等人,2001年)。最佳进针位置对于避免严重副作用以及评估药物无反应或注射部位错误至关重要。虽然向浅表、极易触及的肌肉注射相当容易,但向其他肌肉如髂腰肌注射可能更困难,且难以控制进针以达到最佳注射部位。作为对此的解决方案,我们提出一种超声引导下注射技术。在髂腰肌注射BTX-A的主要适应证是动态髋屈曲畸形,主要由痉挛状态引起,这可能影响行走(在整个步态周期中骨盆前倾增加、终末站立时髋伸展减少、摆动期髋屈曲峰值增加;莫莱纳尔斯等人,1999年)。另一个适应证可能是股骨头脱位(作为注射方案的一部分,该方案还包括内收肌和内侧腘绳肌等其他肌肉),以缓解疼痛、减少护理困难,并可能防止进一步脱位(波尔塔,2000年;福斯特等人,2001年;德勒普朗克等人,2002年;卢比克等人,2002年)。在佩吉特病中,在髂腰肌和内收肌注射BTX-A可能预防固定畸形,这是一个不良预后因素。

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