Kerr S, Crawford M, Currie B, Pracy E, Stacey R, Duffy B
Prince of Wales Children's Hospital, Randwick, New South Wales, Australia.
J Paediatr Child Health. 1992 Dec;28(6):429-31. doi: 10.1111/j.1440-1754.1992.tb02710.x.
Extracorporeal membrane oxygenation (ECMO) has been used at the Prince of Wales Children's Hospital, Sydney for the treatment of newborn infants with life-threatening respiratory or cardiac failure since August 1989. The main indications are that the disease is reversible, the surviving infant is likely to be normal and there is an 80% likelihood of death without ECMO. Eighteen of 19 newborn infants have survived at least 2 months after ECMO. The 15 infants receiving ECMO (nine with meconium aspiration, six with persisting pulmonary hypertension) who did not have a congenital diaphragmatic hernia were normal survivors. One death occurred at 5 months of age from chronic lung disease. Three of four infants with congenital diaphragmatic hernia were discharged following ECMO and appeared normal at 6, 9 and 18 months of age. These results are similar to results from other centres internationally. It appears that ECMO is a useful therapy for near-term newborn infants with otherwise fatal cardiorespiratory failure.
自1989年8月以来，悉尼威尔士王子儿童医院一直在使用体外膜肺氧合（ECMO）治疗患有危及生命的呼吸或心力衰竭的新生儿。主要指征为疾病可逆、存活婴儿可能正常且若无ECMO死亡可能性为80%。19例新生儿中有18例在接受ECMO治疗后至少存活了2个月。15例接受ECMO治疗的婴儿（9例胎粪吸入、6例持续性肺动脉高压）无先天性膈疝，均正常存活。1例于5个月时死于慢性肺病。4例先天性膈疝婴儿中有3例在接受ECMO治疗后出院，在6个月、9个月和18个月时看起来正常。这些结果与国际上其他中心的结果相似。看来，ECMO对于患有其他致命性心肺衰竭的近期新生儿是一种有效的治疗方法。
