Kinkel S, Kaefer W, Reissig W, Puhl W, Kessler S
Orthopaedic Department (RKU), University of Ulm, Germany.
Acta Chir Orthop Traumatol Cech. 2003;70(5):269-73.
Aim of this study was to report the incidence of complications in a consecutive series of revision total hip arthroplasties (THA). Gender and age as a risk factor for the occurrence of perioperative complications in patients undergoing revision THA were analyzed specifically.
All consecutive revision THA (n = 169) for aseptic loosening, which were performed between 1998 and 2002 were evaluated. Our study population had a mean age of 71.7 years and consisted of 65.7% women and 34.3% men. Complete exchange of the primary implant was performed in 49.7% (84/169). The cup was replaced in 66 cases (39.1%) the stem only in 11.2% of patients (19/169).
Retrospective analysis was performed assessing the influence of gender and age on the complication rate by multiple regression models, estimating odds ratios (OR) and their 95% confidence intervals (CI).
Comparable complication rates to those reported in the literature were found. Overall incidence of complications was 29.6% with a fracture rate of 6.5%, dislocation rate of 8.3%, nerve palsy rate of 4.7% and occurrence of thromboembolism in 1.8% of the reported cases. Mortality rate during the observed period was low (0.6%). We were not able to provide statistical evidence for the impact of gender and age on the complication rate.
A comparable complication rate following revision THA to those reported in the literature was found in our study sample. Corresponding to other authors a higher risk of nerve palsy and thromboembolism among women was assessed. The observed correlation of fracture rates and female gender might be attributable to osteoporotic bone in postmenopausal women. Dislocation seemed to be more frequent in older patients, which has been described previously as well. Our low mortality rate in revision THA comparable to previous reports might be due to our short observation period.
Revision THA is associated with a higher risk of complications than primary THA. A predictive value of gender and age in regard to the overall complication rate could not be confirmed which should be considered while deciding about the therapeutic strategy confronted with an aseptically loosened THA. To provide statistical evidence of a correlation between gender, fracture and nerve palsy as well as age and dislocation rates greater study populations are required.
本研究旨在报告一系列连续翻修全髋关节置换术(THA)的并发症发生率。具体分析了性别和年龄作为翻修THA患者围手术期并发症发生的危险因素。
对1998年至2002年间因无菌性松动而进行的所有连续翻修THA(n = 169)进行评估。我们的研究人群平均年龄为71.7岁,其中女性占65.7%,男性占34.3%。49.7%(84/169)的患者进行了初次植入物的完全置换。66例(39.1%)患者更换了髋臼杯,仅11.2%(19/169)的患者更换了股骨柄。
采用回顾性分析,通过多元回归模型评估性别和年龄对并发症发生率的影响,估计比值比(OR)及其95%置信区间(CI)。
发现并发症发生率与文献报道相当。并发症总发生率为29.6%,骨折率为6.5%,脱位率为8.3%,神经麻痹率为4.7%,1.8%的报道病例发生血栓栓塞。观察期内死亡率较低(0.6%)。我们无法提供性别和年龄对并发症发生率影响的统计证据。
在我们的研究样本中,翻修THA后的并发症发生率与文献报道相当。与其他作者一致,评估出女性发生神经麻痹和血栓栓塞的风险较高。观察到的骨折率与女性性别之间的相关性可能归因于绝经后女性的骨质疏松性骨。脱位在老年患者中似乎更常见,这在之前也有描述。我们翻修THA的低死亡率与之前的报道相当,可能是由于我们的观察期较短。
翻修THA比初次THA具有更高的并发症风险。性别和年龄对总体并发症发生率的预测价值尚未得到证实,在决定面对无菌性松动的THA的治疗策略时应予以考虑。为了提供性别、骨折与神经麻痹以及年龄与脱位率之间相关性的统计证据,需要更大的研究人群。