Wing Y K, Hui S H, Pak W M, Ho C K, Cheung A, Li A M, Fok T F
Department of Psychiatry, Prince of Wales and Shatin Hospital, Shatin, The Chinese University of Hong Kong, Hong Kong SAR, China.
Arch Dis Child. 2003 Dec;88(12):1043-7. doi: 10.1136/adc.88.12.1043.
Unlike the adult sleep related disordered breathing (SDB) patients who are typically obese, the relation between obesity and childhood SDB is not clear.
To investigate whether obese children are more at risk of obstructive SDB when compared to normal population, and whether this risk is potentiated by the presence of pharyngeal lymphoid tissue.
Forty six obese children (age 10.8 (SD 2.3) years; BMI 27.4 (SD 5.1)), and 44 sex and age matched normal weight children (age 11.7 (SD 2.1) years; BMI 18 (SD 1.8)) were studied. All children underwent a set of physical examinations (including the upper airways) and sleep studies.
The obese children were different from the normal weight children in terms of type (predominantly obstructive), frequency, and severity of respiratory disturbances. Depending on the criteria used, 26% or 32.6% of obese children had SDB; 2.3% of normal controls had OAI > or =1 and 4.5% had RDI > or =5. Presence of SDB was related to presence of tonsils (size >2; range 0-4) (OR 12.67, 95% CI 2.14 to 75.17) and BMI (OR 1.20, 95% CI 1.08 to 1.33).
Results suggest that obese children are at increased risk of obstructive SDB; the presence of any pharyngeal lymphoid tissue enlargement in obese children should therefore be aggressively managed.
与通常肥胖的成人类睡眠相关呼吸障碍（SDB）患者不同，肥胖与儿童SDB之间的关系尚不清楚。
调查肥胖儿童与正常人群相比是否更易患阻塞性SDB，以及这种风险是否因咽部淋巴组织的存在而增强。
研究了46名肥胖儿童（年龄10.8（标准差2.3）岁；BMI 27.4（标准差5.1））和44名性别和年龄匹配的正常体重儿童（年龄11.7（标准差2.1）岁；BMI 18（标准差1.8））。所有儿童均接受了一系列体格检查（包括上呼吸道）和睡眠研究。
肥胖儿童在呼吸障碍的类型（主要为阻塞性）、频率和严重程度方面与正常体重儿童不同。根据所使用的标准，26%或32.6%的肥胖儿童患有SDB；2.3%的正常对照者OAI≥1，4.5%的正常对照者RDI≥5。SDB的存在与扁桃体的存在（大小>2；范围0-4）（比值比12.67，95%可信区间2.14至75.17）和BMI（比值比1.20，95%可信区间1.08至1.33）有关。
结果表明肥胖儿童患阻塞性SDB的风险增加；因此，肥胖儿童中任何咽部淋巴组织增大的情况都应积极处理。
