[Left ventricular remodeling in chronic heart failure: clinical-morphological parallels].

AIM

To study morphofunctional state of left ventricular and right atrial myocardium in chronic heart failure at tissue, cellular and subcellular levels and to assess relationship between observed morphological changes and echocardiographical characteristics of left ventricular remodeling.

RESULTS AND CONCLUSION

Myocardial remodeling in chronic heart failure was characterized by impaired cellular-stromal balance, enhanced processes of degeneration of cardiomyocytes, lowered energy availability in these cells, and insufficient intracellular regeneration. Fairly close relationship was observed between morphological myocardial changes and echocardiographical parameters of left ventricular remodeling.